One notable scientific breakthrough in recent times that has the potential to overcome the observed disparity in data outcomes due to study cohort heterogeneity is the identification of PCa fusion genes involving the promoter of transmembrane protease serine 2 (TMPRSS2-prostate-specific and androgen-responsive) fused with the coding sequence of Ets gene family members as oncogenic drivers [36,37,38]. Here, TMPRSS2 is linked to posterior cortical atrophy.