Subcellular localization analysis reveals differences in PDLIM7 distribution, with cytoplasmic localization in classical papillary thyroid carcinoma (PTC) and mixed cytoplasmic and nuclear staining in follicular papillary thyroid carcinoma (FVPTC), poorly differentiated thyroid carcinoma (PDTC), and undifferentiated thyroid carcinoma (ATC). The gene discussed is PDLIM7; the disease is differentiated thyroid carcinoma.