Tumor growth, monitored using in vivo bioluminescence imaging, was detected in all mice grafted with GB5-shCTL or GB1-shCTL, whereas no signal was detected in mice grafted with cells depleted for CELF2 expression (shCELF2) even three to five weeks after transplantation (Figure 3G, left and middle panels). Here, CELF2 is linked to neoplasm.