With lymph node metastasis (OR 0.270, 95% CI 0.091–0.801, p = 0.018), high YAP1 expression remained an independently significant parameter with ODX low risk, RS ≤26 (OR 0.373, 95% CI 0.198–0.703, p = 0.002). Here, YAP1 is linked to metastatic malignant neoplasm in the lymph nodes.