Moreover, it has been found that DNMT1 overexpression is correlated with stomach tumor localization, DNMT3 overexpression is correlated with the tumor-node-metastasis (TNM) score, and the concomitant overexpression of DNMT1 and DNMT3A is significantly associated with lymph node metastasis [5,118,119,120,121,122,123]. Here, DNMT1 is linked to neoplasm.