Despite the myriad of papers confirming the involvement of PTEN and PTENP1 in a ceRNA network in cervical cancer [115,121], breast cancer [109,111], gastric cancer [116,122], oral squamous cell carcinoma [106], clear cell renal cell carcinoma [105], and in bladder cancer cells [112], there has been controversy from validation consortiums conducting replication studies [123,124]. This evidence concerns the gene PTENP1 and breast cancer.