SEZ6L and carcinoma: Another study showed a significantly lower expression of the DNMT3A1 and DNMT2 mRNAs, the latter being in agreement with our results, but a higher expression of the DNMT3B1/B2 mRNA isoforms in carcinomas than in low malignant potential tumors, and that DNMT3B1/3B2 mRNA levels were associated with the methylation status of CDH13, MLH-M2B, SEZ6L and MINT31-M1B [37].