Overall, in the context of YY1/RKIP cross-talk in the regulation of tumor infiltration by immune cells, our results show that YY1 and PEBP1 expression scores were anti-correlated with infiltration levels of nTreg cells, B cells, neutrophils, and CD8 naïve T cells, as well as with the infiltration score and CD4+ T cells, Tfh, NK, MAIT, NKT, and Th2 cells. This evidence concerns the gene CD4 and neoplasm.