Differentially from DM types I and II, pancreatogenic DM is well tolerated, being fairly sensitive to insulin administration, and rarely develops ketoacidosis or severe hyperglycemia or hypoglycemia [32], as confirmed also by our study, in which, in all patients manifesting post-operative DM, the hormonal impairment resulted to be well controlled through insulin supplementation, with minimal affection on the quality of life of patients. Here, INS is linked to Hyperglycemia.