POMC and adrenal cortex neoplasm: Trilostane is a synthetic hormonally inactive steroid that competitively inhibits 3β-hydroxysteroid dehydrogenase, resulting in the suppression of the synthesis of cortisol produced autonomously within an adrenocortical tumor or in response to adrenocorticotropic hormone (ACTH) stimulation [1,7,8,9,10].