CRP and rheumatoid arthritis: The current knowledge suggests the presence of specific autoantibodies (rheumatoid factor (RF)anti-citrullinated, anti-carbamylated, and anti-acetylated peptide antibodies) [8], elevated erythrocyte sedimentation rate (ESR), C- reactive protein values [9,10], and tenosynovitis [8] as possible predictors of progression to RA.