A higher level of IL-6 was associated with the presence of carotid plaques (at both UVA and MVA) in our patients, which is consistent with the literature, which shows that IL-6 is strongly associated with the severity of carotid atherosclerosis in hemodialysis patients and that increased circulating levels of IL-6 are independently associated with carotid atherosclerosis progression during the first 12 months of dialysis [37,38]. The gene discussed is IL6; the disease is carotid atherosclerosis.