With regards to OSA, an analysis of 1645 participants from multicenter studies, of whom 65% had detectable levels of hs-cTnT, showed that levels of hs-cTnT were associated with an increasing severity of OSA, as assessed by the respiratory disturbance index (RDI), as well as the risk of death and incident HF in OSA patients, irrespective of the RDI [32]. Here, TNNT2 is linked to obstructive sleep apnea syndrome.