NPPB and diabetes mellitus: Analysis of individual RVF patterns. After adjusting for hypertension, diabetes mellitus, a definite diagnosis of HF (i.e., HF Stage C) and serum creatinine, worsening RVF patterns were associated with higher NT-proBNP serum levels, lower TAPSE/sPAP, larger IVC diameter and higher ePAWP (Figure 3).