Subjects with T1D demonstrated an increase in serum concentrations of IL-1β, IL-1Ra, IL-2Rα, IL-3, IL-6, IL-7, IL-12 p40, IL-16, IL-17A, LIF, M-CSF, IFN-α2, IFN-γ, MCP-1, MCP-3, and TNF-α compared to normoglycemic individuals. The gene discussed is IL1B; the disease is type 1 diabetes mellitus.