In general, these findings are consistent with the literature data on an increase in the levels of circulating IL-1β [28,29,30], IL-6 [29,31,32], IL-12 [29], IL-17A [30,33], IFN-γ [32,34], MCP-1 [29,35], TNF-α [28,29,32,36], and a decrease in IL-4 concentrations [37] in patients with T1D. This evidence concerns the gene IL1B and type 1 diabetes mellitus.