However, previous studies only analyzed the correlation between insulin levels and GBS, while we further adopted more accurate indicators that reflect islet β cell secretion levels and insulin resistance indexes, which can better verify that the severity of insulin resistance in T2DM patients is an independent risk factor for the incidence of GBS, and that the degree of islet β cell secretion is closely related to the incidence of GBS. The gene discussed is INS; the disease is Insulin resistance.