A mostly unexpected resolution of PHP was detected after a bilateral adrenalectomy for Von Hippel–Lindau Disease-related bilateral pheochromocytoma with ectopic (intra-adrenal) PTH expression; this was the case of a 17-year-old teenager admitted for pheochromocytoma-related diabetes mellitus and high blood pressure. This evidence concerns the gene PTH and pheochromocytoma.