CD4 and cryohydrocytosis: One of the first reports by Kornek et al., describing the role of circulating EVs in patients with two different chronic liver diseases, chronic viral hepatitis C (CHC) and MASLD/MASH, identified CD4+ and CD8+ T-cell-derived microparticles (MPs) in the plasma of patients with active CHC and MASLD/MASH [23].