Direct correlations have been found between IL-1 RA and insulin (r = 0.335, p = 0.024), HOMA-IR index (r = 0.311, p = 0.037), weight (r = 0.483, p = 0.001) and between IL 6 and insulin (r = 0.550, p < 0.001), HOMA-IR index (r = 0.532, p < 0.001), weight (r = 0.541, p < 0.001), fasting blood glucose (r = 0.327, p = 0.028). The gene discussed is IL1A; the disease is rheumatoid arthritis.