Patients who developed nosocomial infections had significantly higher levels of SEMA3F (6.0 ng/mL, IQR 4.5–6.4 vs. 4.5 ng/mL, IQR 3.9–5.6, p = 0.0411) and SEMA7A (2.8 ng/mL, IQR 1.90–4.2 vs. 1.3 ng/mL, IQR 0.59–1.9, p = 0.0005). The gene discussed is SEMA7A; the disease is nosocomial infection.