Similarly, the absolute numbers of CD8+ T cells Tc2 and Tc17 CD8+ T cells were elevated in patients with pSS vs. healthy control group (149 cells/1 μL (76; 218) vs. 71 cells/1 μL (59; 113) with p < 0.001 and 7 cells/1 μL (4; 11) vs. 3 cells/1 μL (2; 6) with p = 0.006), while the levels of Tc17.1 was decreased (11 cells/1 μL (7; 18) vs. 14 cells/1 μL (11; 23) with p = 0.036). This evidence concerns the gene CD8A and peeling skin syndrome.