Results of comparisons of the transcriptional activity of the metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) genes using the Kruskal–Wallis test in patients with coronary angiography excluded coronary artery disease (A), patients with coronary artery disease without heart failure (B) and patients with coronary artery disease and heart failure (C) are shown in Figure 5 and Figure 6. This evidence concerns the gene TIMP1 and coronary artery disorder.