During colitis, the E-52862-treated animals presented an overall downregulation in the expression of sensory markers, similar to that observed in the vehicle-treated animals, but in this case, statistical significance was achieved for the expression of CB1, NGF, and TPH1 (all p < 0.05 vs. E-52862-treated animals not exposed to DSS; Figure 10). This evidence concerns the gene NGF and colitis.