Masato’s team examined the levels of hepatic CRP in 100 histologically confirmed NAFLD patients by means of hsCRP and PCR, and the results showed that hsCRP can not only distinguish NASH from pure non-progressive steatosis, but also indicate liver fibrosis in NASH case severity, even after adjusting for age, sex, presence of diabetes, body mass index, and visceral fat [63]. Here, CRP is linked to metabolic dysfunction-associated steatohepatitis.