Similarly, a greater proportion of patients in the PD-L1-positive group presented with characteristics such as deep invasion (35.6% vs. 24.4%, p = 0.004), LVSI (39.7% vs. 25.6%, p = 0.023), and lymph node metastasis (17.1% vs. 7.2%, p = 0.024). This evidence concerns the gene CD274 and metastatic malignant neoplasm in the lymph nodes.