DUX4 and facioscapulohumeral muscular dystrophy: Analysis of MSigDB Hallmark pathways also revealed apabetalone upregulated pathways with the potential to benefit FSHD cells, such as DNA Repair, an important process to counter DUX4-induced damage [52], and WNT Beta Catenin Signaling, previously found to prevent DUX4-associated apoptosis [13].