LGALS3 and myocardial infarction: In our study, we found that M1 macrophages induce the process of EMT in MI-induced cardiac fibroblasts by upregulating the protein expression of galectin-3, N-cadherin, and vimentin and downregulating E-cadherin expression, whereas M2 macrophages upregulate E-cadherin expression and downregulate the expression of galectin-3, N-cadherin, and vimentin.