PLGA nanoparticles encapsulating curcumin and meloxicam alone (nCur and nMlx) and combined (nCur/Mlx) significantly (p ≤ 0.05) raised RBCs and Hb and reduced WBCs in arthritic rats compared to the model group (Table 1), resulting in a delay in anemia onset and immunosuppression. Here, GSTM1 is linked to anemia (phenotype).