Since the discovery of ADGRV1 as a causal gene of type II Usher syndrome [38], a large number of variants have been identified, and, with varying strength of evidence, they have been linked to syndromic or non-syndromic hearing loss as well as to epilepsy (e.g., see https://www.hgmd.cf.ac.uk/ac/index.php (accessed on 30 March 2023); https://www.ncbi.nlm.nih.gov/clinvar (accessed on 15 May 2023)). Here, ADGRV1 is linked to hearing loss disorder.