FGL2 is characterized by complexity and multifunctionality and is involved in cardiovascular diseases and conditions, including the progression of pulmonary hypertension [38], COVID-19-generated thrombosis [40], autoimmune myocarditis, and dilated cardiomyopathy in mice [41], and in an AF porcine model [42]. This evidence concerns the gene FGL2 and pulmonary arterial hypertension.