We have presented three sets of biomarkers that were significantly associated with T2D in postmenopausal women, i.e., age, glucose and insulin (i.e., age-glycometabolic-related factor), HDL-c, LDL-c and TG (i.e., lipid-related factor) and WC, hsCRP and [25(OH)D] (i.e., obesity-inflammation-related factor). This evidence concerns the gene INS and type 2 diabetes mellitus.