TGFB1 and oral cavity squamous cell carcinoma: We can thus assume that lysates from our IDG-SW3 osteocytes and oral squamous cell carcinoma cell lines HSC2 and TR146, as well as from gingival fibroblasts, possess a TGF-β activity that might serve as a damage-associated molecular pattern driving the expression of IL11 by the gingival fibroblasts—a hypothesis driven by the increasing recognition of IL11 as a potential master regulator of oral health and disease.