In another propensity-matched analysis of 282 patients with acute ischemic stroke enrolled in the International Stroke Perfusion Imaging Registry (INSPIRE) who achieved complete reperfusion after IV tPA or thrombectomy, there was increased sICH in the IV-tPA-only group with an infarct core >30 mL compared to those with EVT (20% vs. 3%, p = 0.008); of note, the majority of the EVT group also received IV tPA [17]. Here, PLAT is linked to Stroke.