Other factors such as sex (p = 0.174), BMI (p = 0.939), Tg (p = 0.128), anti-Tg (p = 0.270), anti-TPO (p = 0.112), Graves’ disease (p = 0.369), Hashimoto’s disease (p = 0.432), and the size of the dominant nodule (p = 0.285) did not significantly affect the discrepancy between US-TV and IO-TV. Here, TPO is linked to Hashimoto thyroiditis.