CRP and Hepatic fibrosis: It is peculiar that, at variance with WBCs and platelets which express cellular inflammation promoting liver fibrosis, CRP circulating levels did not change after VLCKD, suggesting that the possible anti-inflammatory activity of VLCKD is effective on WBC and platelet production, but not on the liver synthesis of hs-CRP, an acute phase protein that may show a non-specific rise within six hours of an inflammatory stimulus.