PCOS patients show increased inflammatory markers, C-reactive protein (CRP), interleukin 18 (IL-18), tumor necrosis factor α (TNF-α), interleukin 6 (IL-6), white blood cell count (WBC), monocyte chemoattractant protein-1 (MCP-1), and macrophage inflammatory protein-1α (MIP-1α). The gene discussed is TNF; the disease is polycystic ovary syndrome.