NFE2L2 and swine influenza: The PR8/H1N1 virus infection led to a 1.5-fold lowering of Nrf2 expression, which was counteracted by the HOP extract and ECP/HOP without the effects of ECP (Figure 13E,F): indeed, about a 1.2-fold increase in Nrf2 expression with respect to the levels of the infected control was achieved.