Consistently, and unlike aldolase B KO mice, which failed to thrive on ethanol, AldoB/Khk DKO mice had greater body weight gain (Figure 5J) with improved liver injury, as denoted by reduced inflammation, steatosis (Figure 5K) and overall, a significantly lower injury score (Figure 5L) and levels of transaminases ALT and AST in plasma (Figure 5M,N). Here, KHK is linked to steatosis.