For CD163, there was a significant effect of obesity (F (1, 80) = 73.79; p < 0.0001) and OEA-DS administration (F (1, 80) = 11.87; p = 0.0009), and a significant interaction effect of these factors (F (1, 80) = 5.548; p = 0.0209). Here, CD163 is linked to obesity due to melanocortin 4 receptor deficiency.