IGHE and allergic disease: Clinically, avoiding foods containing shrimp can help patients with shrimp allergy avoid further sensitization and IgE-mediated reactions, but it is unknown whether environmental exposure to HDMs or insect-derived tropomyosin or the fish parasitic nematode Anisakis simplex tropomyosin could result in further priming and the re-stimulation of a shrimp-specific allergic response [17].