ULK1 and hereditary clear cell renal cell carcinoma: An increased expression of TRPM3 in renal cell carcinoma leads to Ca2+ influx, which elicits the activation of CaMKII, 5′-AMP-activated protein kinase (AMPK), and Unc-51-like autophagy-activating kinase 1 (ULK1), as well as the formation of phagophore [147].