TF and alkaline phosphatase measurement: While GlycA has not been studied in AP previously, the recognition of GlycA as an inflammatory biomarker of AP in our study makes pathophysiological sense because each of the five acute phase glycoproteins that comprise GlycA (α1 acid glycoprotein, haptoglobin, α1 antitrypsin, α1 antichymotrypsin, and transferrin) has been individually studied over the years and shown to be associated with AP [28,29,30,31,32,33].