HK1 and neoplasm: Furthermore, tumor tissues originating from AsPC-1 cells with tRF-19-Q1Q89PJZ knockdown showed higher HK1, Ki-67, and PCNA expression levels than those originating from control cells, whereas HK1, Ki-67, and PCNA expression levels were lower in tumor tissues derived from AsPC-1 cells overexpressing tRF-19-Q1Q89PJZ (Figure 7D).