The DUB proteins USP1, OTUB1, UCHL5, USP7, and PSMD14 were reported to contribute to double-strand break repair, USP1 to Fanconi anemia pathway, USP1 and USP7 to translesion repair, USP7 and USP47 to base excision repair, and USP7 and USP45 to nucleotide excision repair [83]. This evidence concerns the gene USP45 and Fanconi anemia.