GSTM1 and thalassemia: In 2019, Malaysian Thalassaemia Registry reported a total of 8178 registered thalassaemia patients, of which majority of them suffered from HbE/β-thal; followed by β-thal major (β-TM); Hb H disease; β-thal intermedia (β-TI); and others, with the percentage of 35.19%, 32.66%, 19.48%, 9.02%, and 3.64%, respectively [22,23].