The results of genotypes and alleles of SIRT1 rs3818292, rs3758391, and rs7895833 in MS and control groups between different ages (40 or younger, and over 40 years old) indicated that the rs3758391 CC genotype was less frequent, whereas that of the CT genotype was higher in the MS group than in the control group in the younger participants (56.7% vs. 38.6%, p = 0.004; and 35.0% vs. 53.8%, p = 0.003, respectively). This evidence concerns the gene SIRT1 and myeloid sarcoma.