GPT and hepatocellular carcinoma: In the subgroup of HBeAg-negative subjects with HBV DNA values between 2000 and 19,999 IU/mL (intermediate viral load (IVL)) and normal values of ALT, HBcrAg values ≥ 10 KU/mL have indicated patients to be at an increased risk of HCC (odds ratio, 6.29; confidence interval, 2.27–17.48).