When subdivided our patients according to gender and type of skin disease (PsO vs. AD), we found that men with AD exhibited higher CAT activity than men in the PsO group, whereas AOPP levels were lower in women with AD in comparison with men with AD which is opposite to Chen et al. [12] who did not confirm a gender difference in urinary 8-OHdG in children with AD. The gene discussed is CAT; the disease is Alzheimer disease.