The increments of rAST and rALT catalytic activities (compare group II with I in Table 5) by 7.64- and 5.71-fold, respectively, were indicative of the hepatocyte’s membrane damage by CCl4 administration, revealing the early symptoms of hepatocellular toxicity and cirrhosis [159], whereas the increase of rALP and rγ-GT catalytic activities (compare group II with I in Table 5) by 2.06- and 4.94-fold, respectively, indicated bile problems [161]. This evidence concerns the gene ERRFI1 and Cirrhosis.