Under basal conditions, 8-isoprostane release is greater in GDM SAT, and stimulation with LPS and HX/XO increases its release in SAT and VAT as well as TNF-α, IL-6 and IL-8 release, while there is no change in SAT and VAT antioxidant gene expression under basal conditions and in response to HX/XO [55,56]. Here, IL6 is linked to gestational diabetes.